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This report provides information on a free, full-text paper titled "an anatomical investigation of pig peripheral nerve and its potential utility in nerve tissue engineering." The peripheral nervous system, which links the central nervous system to the rest of the body, is made up of neurons and nerve fibers. Aranyosi contends that it consists of mental states as opposed to merely incidental causes of their existence (21-32). Natural and artificial proteins, according to Sen and Nilsson, are closely similar (146-147). Nature uses small structural proteins to create flexible and varied matrixes. Blending is one of the tactics used to create less complex material systems and increase material uniformity. Technology does provide knowledge of tissue functioning in vitro and Vivo. This study will provide a new protein materials platform with direct relevance to tunable tissues repair and treatment of diseases

The primary goals of conducting research were to analyze the interactions between protein-protein through the computational methods and understand the mixture verification processed through thermal analysis. Explore how to make protein alloy solutions, making of variables, evaluate the electrical materials with circuit coatings and understand the pharmaceutical materials for drug use and delivery. Information for designing the next generation multi-functionalism biomaterials based on different protein alloys can be done using these methods.The changeable aspects are natural proteins and can be joined to form an attraction force between them

In this research, two types of structural proteins were used to show the general protocols of producing various protein alloy biomaterials. The methods applied to obtain the intended results were manipulation of these rules. These procedures included protein interaction predictions and simulations, fabrication of protein alloy systems and for electrical optical and pharmaceutical application, and production of alloy proteins solutions. Protein interaction predictions involved bioinformatics analysis of protein molecules, computational simulation of protein alloys system through a prescribed procedure. The protocol of production of protein alloys solutions by use of the two protein samples. The other procedure was a fabrication of variable protein alloy materials. This involved the confirmation of mixture prediction by thermal analysis, fabrication of optical materials by protein alloys, fabrication of electrical circuits on protein alloys materials and fabrication of pharmaceuticals materials by protein alloys. The challenge of conducting the study was the lack of enough funds to carry out effective research. The problems of lack of resources and facilities hindering the wider research. The availability of the natural proteins also is minimal.

The hypothesis of my research article was whether the porcine peripheral nerves have a microstructure same as that of a rat and that it is similar to that of a human. The significance of the study was to ascertain that the porcine nerves might have used as a nerve graft provide support and guidance to regeneration axons. Similar to the anatomy of human nerve. Silks obtained from different worm species, collagens, plant proteins and keratins from hair and wool. They have features that facilitate the formation of self-assembled macroscopic structures used in making biopolymer materials.

The obtained results were that protein- protein interactions has electrostatic attractions, hydrogen bonding making, hydrophobic-hydrophilic interactions as well as dipole solvent, counter ion, and entropic affects the specific domains of the proteins. Fundamentally, computational simulations can predict effects of these interactions. These data results were presented in diagrams and figures to enable dynamic analysis. Previous research shows that different soluble and insoluble cancer drugs are directly used in protein alloy material. Mixing of cancer drugs with protein alloy materials as they were very toxic. Patients are cured through controlled release of cancer drugs finally recovers without additives in their body. Besides, some other experiments were carried out to relate the expected results and actual findings. This included thermal analysis model used for verifying miscibility of blended protein systems and the general steps used to produce a protein alloy material.

Verification of the miscibility of blended proteins in producing alloys is the most important procedure. Alloy properties are confirmed through Experimental thermal analysis. Flory-Hugging’s lattice model explains the protein-protein interactions. During this mixing between the solvent and the solute directs the miscibility of the blend. There are three levels of miscibility degrees, which include fully miscible, metastable, and immiscible.

In conclusion, new generations of protein alloy materials are made and fabricated into different medical devices like screws, plates, and gels. Various properties of proteins such as elasticity and bio-durability are regulated by controlling the ratios of mixing components. The programmable nature of proteins allows Vivo to a viable avenue for alloys in future. Hughes argues that proteins are the basis of biotechnology (p.27).This property of protein will facilitate post repair surgical retrieval avoidance. Generally, this article gives protocol review of how devices are fabricated to be of benefit in the medical field.







Work cited

Aranyosi, István. The Peripheral Mind: Philosophy of Mind and Peripheral Nervous System. New York [etc.: Oxford University Press, 2013. Print.

Hughes, Andrew B. Amino Acids, Peptides, and Proteins in Organic Chemistry. Weinheim: Wiley-VCH, 2012. Internet resource.

Sen, Srikanta, and Lennart Nilsson. Thermostable Proteins: Structural Stability and Design. Boca Raton: CRC Press, 2012. Print.











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